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 4.7 Rating (4,175 Reviews)

#1 Niacinamide & Panthenol Gel Cream!

345 Relief Cream™

345 Relief Cream™

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Soothing Care

Skin Barrier

Bright Skin

Deep Hydration

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345 Relief Cream™

345 Relief Cream™

Regular price $37.99
Regular price $37.99 Sale price $64.00
SAVE 40% Sold out

Frequently Asked Questions

1. What does 345 Relief Cream™ do?

Our lightweight gel-cream hydrates deeply while soothing and strengthening sensitive skin. With niacinamide to brighten and even tone, and panthenol to calm irritation, it helps restore your skin barrier and keep your complexion balanced and healthy.

2. When should I use it?

Apply morning and night after cleansing. It’s perfect for:

Daily hydration and soothing

Calming redness or sensitivity

Supporting an even, radiant complexion

3. Will it make my skin greasy?

Not at all. Its fast-absorbing gel texture delivers intense hydration without heaviness or shine. Ideal for all skin types, including oily and sensitive skin.

4. Is it safe for daily use?

Absolutely! 345 Relief Cream™ is dermatologically tested, non-comedogenic, and free from parabens, artificial fragrances, and harsh irritants—perfect for everyday skincare.

5. What makes 345 Relief Cream™ different?

With a clean, effective formula powered by niacinamide + panthenol, it delivers what your skin truly needs—hydration, soothing, and barrier support—without unnecessary fillers or fragrances.

6. Is there a guarantee?

Yes! You’re covered by our 30-day, no-questions-asked guarantee. If you don’t love how your skin feels, we’ll give you a 100% refund—simple as that.

About Us

Formulated by Science. Built for Life.

At SYNRG, we don’t chase trends—we follow the research. Our mission is simple: to create high-performance supplements that actually work. Every ingredient we use is backed by clinical science, and every formula is crafted with care, clarity, and uncompromising standards.

Wellness, Simplified

We believe wellness should feel powerful—not complicated. Whether it’s calming the mind, fueling sharper focus, or optimizing recovery, our products are designed to support your body’s natural balance, without shortcuts or synthetic fillers.

What Sets SYNRG Apart

Clean, effective formulas

Clinically studied ingredients

GMO-free, gluten-free, lab-tested

Formulated for results—not hype

Invest in Your Longevity

With SYNRG, you're not just supplementing your health—you’re investing in your longevity.

30-Day Money Back

Try SYNRG Risk-Free

We’re confident in the science, the purity, and the results behind every supplement we make. That’s why we offer a 30-day, no-questions-asked money-back guarantee.

If you don’t feel a difference in your focus, calm, sleep, or overall well-being, just let us know.

We’ll refund your purchase—no hassle, no stress.

Because wellness should come with confidence.

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Why 345 Relief Cream?

Here are four compelling reasons why someone should take SYNRG Hydrates, Soothes, Brightens, Restores, Protects

Deep Hydration

Provides intense, long-lasting moisture that keeps your skin soft, supple, and refreshed throughout the day without feeling heavy or greasy.

Soothes Sensitivity

Enriched with panthenol to calm irritation, reduce redness, and relieve discomfort, making it perfect for sensitive and reactive skin.

Brightens Complexion

Niacinamide works to even out skin tone, minimize dullness, and restore a healthy, radiant glow for a more youthful appearance.

Strengthens Skin Barrier

Helps repair and protect the skin’s natural barrier, shielding it from dryness, environmental damage, and external stressors.

 
 

Join thousands of people who have seen life-changing results with our product.

  • Best Moisturizer Ever!

    I’ve been using 345 Relief Cream™ for just two weeks, and my skin has never felt this good! It deeply hydrates without feeling greasy, calms my redness instantly, and gives my face a natural, healthy glow. The lightweight gel texture absorbs so fast — perfect under makeup and for my sensitive skin.I’ve tried so many moisturizers before, but this one is truly next level. Highly recommend to anyone struggling with dryness, irritation, or dullness.

    Emily R. – Austin, Texas

  • My Skin Finally Feels Healthy!

    I started using 345 Relief Cream™ about a month ago, and the difference is amazing! My skin used to feel dry and irritated, but now it’s hydrated, calm, and glowing every single day. The lightweight gel texture absorbs quickly and doesn’t leave any greasy residue, which I love.Even my redness has gone down, and my complexion looks so much smoother. I finally found a moisturizer that actually delivers on its promises. Highly recommend it to anyone with sensitive or reactive skin!

    Sarah M. – Denver, Colorado

  • A Game-Changer for My Skin!

    I’ve been using 345 Relief Cream™ for six weeks now, and I’m blown away by the results! My skin feels incredibly hydrated, soft, and nourished without any greasy residue. It calms my sensitivity almost instantly and has made my complexion look smoother and brighter.I love that it absorbs quickly and works beautifully under makeup. At my age, finding a moisturizer that truly delivers is rare — but this one exceeded my expectations. Highly recommend it to anyone looking for healthy, glowing skin!

    Linda K. – San Diego, California

     
     

    Our happy customers aren't just reviews;
    they're living proof that our formula delivers real results.

    96%

    Boost of energy within the first week of use.

    92%

    Reduced mental fatigue within two weeks of use.

    92%

    Reduced mental fatigue within two weeks of use.

    0%

    Zero reported side effects after consistant use.

    30-Day Money-Back Guarantee

    Made In U.S.A

    Free Of Side Effects

    3 Years Of Research

    Made In U.S.A

    Free Of Side Effects

    3 Years Of Research

    Made In U.S.A

    Free Of Side Effects

    3 Years Of Research

    Made In U.S.A

    Free Of Side Effects

    3 Years Of Research

    Made In U.S.A

    Free Of Side Effects

    3 Years Of Research

    Made In U.S.A

    Free Of Side Effects

    3 Years Of Research

    Made In U.S.A

    Free Of Side Effects

    3 Years Of Research

    Made In U.S.A

    Free Of Side Effects

    3 Years Of Research

    Made In U.S.A

    Free Of Side Effects

    3 Years Of Research

    Made In U.S.A

    Free Of Side Effects

    3 Years Of Research

    Made In U.S.A

    Free Of Side Effects

    3 Years Of Research

    Made In U.S.A

    Free Of Side Effects

    3 Years Of Research

    🔒 The SYNRG Guarantee

    We stand by the power of healthy, radiant skin. That’s why every purchase of 345 Relief Cream™ is backed by our 30-day money-back guarantee. Experience noticeable improvements in hydration, soothing sensitivity, and restoring your skin’s natural glow — or receive a full refund, no questions asked.

    You’ve got nothing to lose — except dryness, redness, and irritation.

    Trustpilot reviews

    Excellent 4.8 / 5

    • My Skin Finally Feels Calm!

      I’ve struggled with sensitive skin for years, and 345 Relief Cream™ is the first product that actually works! It soothes my redness instantly and keeps my skin hydrated all day without feeling heavy. My complexion looks brighter, healthier, and more balanced. I’m finally confident going makeup-free. Love it!

      Jessica L., Seattle, Washington

    • Best Moisturizer I’ve Ever Used

      This cream is a game-changer! The lightweight gel texture sinks right in, leaving my skin soft and fresh. My dry patches disappeared in less than a week, and my face feels silky smooth. Plus, no greasy residue at all! It’s perfect for hot, humid weather like Florida’s. Highly recommend!

      – Amanda R.,Miami, Florida

    • Perfect for Sensitive Skin

      My skin reacts to almost everything, but 345 Relief Cream™ has been a lifesaver. It calms irritation, reduces redness, and makes my skin feel stronger and healthier. I love that it’s fragrance-free and super gentle, yet so effective. I’ll never go back to my old moisturizers!

      – Natalie S., Chicago, Illinois